A. Spleen and liver
B. Heart and brain
C. Kidneys and lungs
D. Lungs and heart
🧠 Explanation:
Malaria mainly affects the spleen and liver because the parasite multiplies in liver cells and impacts red blood cells filtered by the spleen. “Organs” is a noun; “affected” is a past participle verb. Alternatives like “kidneys” are not primary targets. Knowledge is vital for medical treatment and disease control.